High Resolution 3D Reconstructions of entire brain with BrainMaker

Scitech is proud to introduce BrainMaker by MBF
Bioscience.Used in applications in
Neuroscience research, BrainMaker generates high-resolution 3D reconstructions
from serial sections imaged with whole slide scanners and research microscopes.

Images are loaded into BrainMaker and it
automatically detects the individual sections on each slide, and then aligns
the sections to create the full 3D image reconstruction of the entire brain (or
any organ). At a glance users can see the location of all neurons expressing a
particular gene, visualise axonal projections of specific neurons within the
full anatomical context.

If you mount a section upside down, BrainMaker will
automatically correct it during the alignment process. BrainMaker uses
innovative computational algorithms to align image features found in multiple
serial sections. If additional adjustments need to be made to the automatic
alignment, researchers can easily edit the 3D reconstruction.

BrainMaker allows you to analyse the size and shape
of neurons within the 3D reconstruction using Neurolucida 360, or analyse the
number of neurons or the volume of a lesion with Stereo Investigator. Reconstructions
created with BrainMaker can be stored, viewed, and shared with Biolucida –
MBF’s platform for organising and sharing big image data.

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