Particle & Surface Sciences Australia reports on the latest news from NanoSight UK, about how Nanoparticle Tracking Analysis NTA is being used in the research project ‘Engineering of Biomolecules’ at the Lorraine University based in Nancy.
Dr Jordane Jasniewski, who works at the Laboratory of Biomolecules Engineering (LIBio) at Lorraine University, Nancy, and teaches Food Chemistry at ENSAIA, an engineering school, is a member of the research team working on the engineering of biomolecules to understand their structure and function to help develop new molecular architectures for application in the areas of foods & agrichemicals, nutrition, pharmacology and cosmetics.
The expertise of LIBio allows the study of stabilisation, functionalization and targeting of active molecules such as probiotics, antibacterial peptides, phenolic antioxidants and polyunsaturated fatty acids (PUFAs). Based on vectors of extremely rich marine DHA (an omega-3 fatty acid), new dairy matrices, phospholipids and biopolymers are being developed.
Describing the reasons for his selection of NTA for the measurement of the hydrodynamic diameter, Dh of his nano-emulsion samples, Dr Jasniewski says that their samples, which include polysaccharides, milk proteins and lecithins are polydisperse. Having used dynamic light scattering, DLS without success, they decided on NTA as it can make measurements on a particle-by-particle basis and does not need the refractive index to determine Dh. Additionally, the research team can also readily measure the concentration of their samples, helping to produce data in a convenient way to export and use for further study.
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