Particle & Surface Sciences announces the release of Zeta Potential Analysis applying Z-NTA, particle-by-particle characterisation of surface charge.
Zeta Potential Nanoparticle Tracking Analysis (Z-NTA) adds measurement of surface charge to simultaneous reporting of size, composition, fluorescence and count.
Similar to NTA, the core of NanoSight’s nanoparticle measurement systems, the Z-NTA collects data on a particle-by-particle basis.
The simultaneous multi-parameter nanoparticle characterisation cannot be done using conventional methodologies.
Key features of Z-NTA nanoparticle characterisation:
- Zeta potential is measured particle-by-particle simultaneously for the complete sample population to provide data that is number weighted, not intensity weighted
- Size and light scattering intensity are also reported
- Polydisperse and complex suspensions are readily characterised
- No labelling is required but a fluorescence mode option is available to further differentiate suitably-labelled sub-populations
- All data sets are validated by real-time observation of particles moving under both electrophoretic and Brownian motion
- Variations in zeta potential with size are analysed with positively and negatively charged particles being reported separately even when they exist together
- Sub-populations of similar-sized particles of different materials, differentiated by their tendency to scatter light are separately reported and counted
- Changes in Zeta Potential distribution with pH, concentration and temperature may be studied
- Aggregation and flocculation may be studied quantitatively in real-time
- Suitable labelling can highlight one sub-population for analysis despite high background noise
NanoSight’s nanoparticle characterisation tool finds application in various fields from the life sciences through to the materials sciences.
NanoSight has installed more than 300 systems worldwide as NTA-based characterisation becomes increasingly accepted as the technique to quantitatively study nanoparticles.