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NanoSight NTA system for nanoparticle characterization from Particle & Surface Sciences

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article image National Physical Laboratory uses NanoSight’s NTA system

Particle & Surface Sciences  introduces the NanoSight NTA system for nanoparticle characterization using the LM-10. NanoSight reports that research organisations around the world routinely look at emerging techniques to evaluate their performance for the quantitative characterization of nanomaterials.  

Nanoparticles are a current area of intense scientific research, as they are a bridge between atomic and bulk structures. National Physical Laboratory, UK is coordinating a network of European national metrology institutes to provide new traceable standards and procedures to determine the size, shape and distribution of nanoparticles with an accuracy of better than 1nm.  

Methods used to investigate the particle size, shape and physical properties include Electron Microscopy (SEM and TEM), Dynamic Light Scattering (DLS), Nanoparticle Tracking Analysis (NTA) and Atomic Force Microscopy (AFM).  

Working as part of the Materials team at the National Physical Laboratory, UK, Dr Alexandre Cuenat is measuring and modelling materials interactions at the nanoscale.  

For Dr. Cuenat, working with NanoSight’s unique NTA methodology to study nanoparticles in liquids shows particular bonuses such as ruggedness, ease of use and reproducibility.  

The fact that NTA images, counts and sizes individual particles means it produces size distribution that cannot be observed otherwise. Dr. Cuenat says that NTA is useful when studying polydisperse materials in the range of ~20nm up to particles of one micron.  

NPL has looked at a variety of calibration materials such as zinc oxide, silica, gold and silver nanoparticles and has successfully characterised these even when problems with sample agglomeration have been observed.  

NanoSight has benefited from this recognition by NPL since traceability of results and the development of standard operating practices are becoming central to success with new methods being developed for life sciences or materials applications.  

As NanoSight CEO, Jeremy Warren observes, more and more of their users are looking to extend the use of NTA beyond the research environment into routine analytical and quality assurance testing.  

NanoSight has installed more than 300 systems worldwide in applications ranging from the life sciences through to materials sciences as NTA-based characterization becomes increasingly accepted as the technique to quantitatively study nanoparticles.

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