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Micromeritics BET and surface area analysers available from Particle & Surface Sciences

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article image Micromeritics ASAP 2020 accelerated surface area and porosity analyser

Particle & Surface Sciences  Australia distributes the Micromeritics range of BET and surface area analysers throughout Australia and New Zealand.

The BET surface area technique is a useful tool for determining the source of batch-to-batch variation during the processing of pharmaceutical powders.

Scientists in today’s pharmaceutical development environment are seeking new analytical test methods to help determine the sources of variability in all aspects of drug development and production. Pharmaceutical scientists for instance, needing to identify and quantify batch-to-batch variation in the processing of powders can use the BET surface area technique to help provide accurate answers.  

Different batches of the same APIs can exhibit different physical and mechanical properties, making it difficult to determine the source of batch-to-batch variability of the APIs.  

Researchers at Novartis Pharmaceutical Corporation, East Hanover, NJ have discovered that BET surface area can help them determine batch-to-batch variability. Novartis scientists used a Micromeritics ASAP 2020 accelerated surface area and porosity analyser to characterise different batches of API that exhibited different flow properties.  

Finding that the amorphous content of the batches varied, the scientists were able to conclude that the varying amorphous content of the batches was the source of the variability in flow behaviour.  

These Novartis findings strongly support the BET surface area test method as an important tool in the investigation of batch-to-batch variation and their overall development and production process.  

Micromeritics manufactures a broad line of automated analytical laboratory instruments that measure the physical characteristics of powders and solids for fundamental research, product development, quality assurance and control, production, and process control applications.  

Particle & Surface Sciences also offers a wide-ranging programme of support solutions including installation and service of all instruments by factory trained technicians in addition to an analytical laboratory.

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